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What Is Hyperdiluted Radiesse?
Aug 29 2023
Reading Time: 4 Minutes
Author: Patricia Pezzano
Growing older is part of life.
But that doesn’t mean we have to look the part!
Regenerative aesthetic treatments can help tighten, tone, and rejuvenate aging skin.
They do this without invasive surgery.
Hyperdiluted Radiesse® is one of these treatments.
Radiesse® is a Health Canada and FDA-approved injectable dermal filler.
It is indicated for immediate volume replacement.
It also stimulates collagen and elastin production in a patient’s skin.
It is made from calcium hydroxyapatite (CaHa) gel microspheres.
It can treat wrinkles or folds, restore lost volume, and provide contour to the face.
Unlike hyaluronic acid fillers, Radiesse® has a biostimulatory effect.
It triggers collagen production in the skin where it is injected.
Hyperdiluted Radiesse® refers to Radiesse® diluted with sterile saline solution.
This dilution process results in a much thinner, more fluid product.
It contains fewer calcium hydroxyapatite (CaHa) gel microspheres per unit of volume.
The fluidity makes it suitable for injecting into other areas.
These areas include the neck or back of the hands.
Hyaluronic fillers are not always appropriate there.
Keep reading to learn more about this exceptional treatment.
Learn about its many benefits and who is an ideal candidate.
How Does Hyperdiluted Radiesse® Work?
Medical aesthetic clinicians administer hyperdiluted Radiesse® using a specialized injection technique.
They strategically place small amounts of the diluted solution into specific treatment areas.
They often use a microcannula or fine-gauge needle.
Once injected, hyperdiluted Radiesse® provides immediate volume correction.
It also stimulates collagen production within the treatment areas.
Collagen is a protein responsible for skin elasticity and firmness.
The CaHa microspheres serve as a scaffold for collagen growth over time.
This allows the skin to create its own volume.
After treatment, skin texture, laxity, wrinkles and facial lines gradually improve.
The CaHa is resorbed, leaving new collagen in its place.

Hyperdiluted Radiesse® Treatment Areas
Hyperdiluted Radiesse® is generally performed in areas where skin laxity is a concern.
These areas include:
- Abdomen
- Neck wrinkles or lines
- Upper arms
- Aging hands
- Knee lines
- Decolletage
- Buttocks with cellulite dimples
- Mid and lower face
Who Is the Ideal Candidate for Hyperdiluted Radiesse®?
Patients in good health should be able to receive hyperdiluted Radiesse® injections.
This is especially true if they have concerns with skin texture, skin laxity, wrinkles, or cellulite.
Patients may not be a good candidate if they:
- Have allergies to any substances in the filler
- Have any skin infections
- Have an autoimmune disease
- Are pregnant or breast-feeding
- Have a history of keloid scarring
There is no age requirement for the treatment.
However, most who request this enhancement are typically 50 or older.
The regenerative effects are best observed in patients with visible signs of aging.
How Effective is Hyperdiluted Radiesse?
Hyperdiluted Radiesse® treatment sessions typically take 15 to 20 minutes each.
After that, there is initial improvement in volume and minimal downtime.
The collagen-stimulating effects of hyperdiluted Radiesse® begin about a month after treatment.
They will continue to improve for at least six months.
Maintenance may be required in some areas to combat advanced signs of aging.
Two to three treatment sessions are likely needed for optimal results.
These sessions should be spaced one to two months apart during the first year.
The number of treatments depends on the patient’s volume loss and skin laxity.
For follow-up treatments, one session every 12 to 18 months is recommended.
This ensures optimal skin firming effects are maintained.

Potential Risks and Side Effects
Patients might experience minor side effects and mild discomfort for up to a week after treatment.
Excessive heat and direct sunlight should be avoided for 24 hours after each session.
Like any regenerative aesthetic treatment, do not touch or massage the treated area.
This helps to avoid filler migration or other complications to the treated skin.
Temporary side effects may include bruising at the injection site, itching, pain, redness, or swelling.
Those who receive this injectable treatment in their hands may encounter slight difficulty with movement.
They may also have temporary loss of sensation, lumps, or nodules.
Those allergic to any substances in hyperdiluted Radiesse® should proceed with caution.
These substances include lidocaine or saline solution.
If a patient suspects pregnancy or is breast-feeding, they are not a candidate.
Professional injectors should always conduct a thorough consultation.
They should also perform a patient risk assessment before any skin rejuvenation treatment.
This ensures all variables are considered.
Learn Innovative Injectable Practices at APT Injection Training
Hyperdiluted Radiesse® is more than just a product.
It is a revolution in aesthetic medicine.
It represents a breakthrough in achieving natural-looking results.
It offers unparalleled safety and efficacy.
Now you know the benefits of hyperdiluted Radiesse® for qualified patients.
It is time to learn how to inject this dermal filler.
Incorporate the treatments into your practice.
The best way to stay ahead is to enroll in an APT Injection Training course.
At our world-class training center in Ontario, students get hands-on experience.
They work with live models and get coaching by experts in the industry.
Call us today for more information about our programs.
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